Why did sir isaac newton refuse a glass of wine before sitting down to formulate the rules for differentiation?

"He knew better than to drink and derive"

Isaac Newton was known to be a passionately focused introvert who could go without sleep for days and live on bread and wine but refused a glass of wine before formulating the rules for differentiation because he did not want to cloud his thinking.

space exploration has led to the development and technological improvement of many everyday items. (if this answer is wrong i will find the right answer) : )