Sickle Cell anemia is a recessive trait that causes blood cells to be misshaped. A woman who has no history of sickle cell anemia marries a man whose father had sickle cell anemia. What are their genotypes?

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Explanation:

Let us assume the sickle cell anemia allele to be S and the alternate, non-sickle cell allele to be A.

Since the woman has no history of sickle cell in her family, she is totally free from the trait and, hence, would have the genotype of AA.

The man's father had sickle cell anemia. This means that the man has, at least, one sickle cell allele in his genotype with the other allele depending on the genotype of his mother. Hence, the man can be AS or SS depending on the genotype of his mother.

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