You discover a pattern of a 20 amino acid sequence at the C-terminus of over 50 proteins in an organism. You hypothesize that this amino acid sequence is a signal sequence for localization into a specific organelle or cell compartment, but you don't know which one. How might you use microscopy to investigate the location of proteins with this unique C-terminus sequence?
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You discover a pattern of a 20 amino acid sequence at the C-terminus of over 50 proteins in an organ...
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