What effect might high temperature or irregular pH levels have on facilitated diffusion?

  The facilitated diffusion is a type of passive transport affected by different factors including the temperature and the pH level. The facilitated diffusion process is produced by proteins that enable the movement of molecules between both sides of the cell membrane.  

   The pH level depends on the ion gradient and this factor modifies the diffusion rate of the buffers between both sides of the cell membrane. Moreover, the temperature is a factor that modifies the ionic charge of molecules, as well as the structure and the porosity of pores that facilitate the interchange between both sides of the cell membrane