Kallymashuupp esta es otra cuenta

1. la ruta arqueologica2.la ruta artesanal3.la ruta paraiso artesanal  4.la ruta de las flores5.la ruta sol y playa6.la ruta de la paz 

The correct answer is
1. black death

a deadly plague that swept through europe between 1347 and 1351, it killed one third of european population, but the left food supply give chances to survivors for advancement.

and

2. smallpox

an eradicated virus that used to be contagious, disfiguring, and often deadly.