How does a bacteria’s resistance to an antibiotic first arise?

when the outside temperature is too cold, an endothermic animal can generate heat by shivering. endothermic animals must eat much more often than ectothermic animals since it takes energy to maintain a constant body temperature.

ancient india is often called the harappan civilization because one of the ancient cities was called harappa. harappa was just one of 1500 cities in the indus river valley. another well-known city is called mohenjo-daro. historians estimate ancient india to be the biggest of all four early civilizations.