What effect has “increasing antibiotic use in the united states” had on people’s microbiomes?

The increasing antibiotic use in the United States has reduced the diversity ofpeople’s microbiomes.
Antibiotics are known to kill various form of Bacterias (which considered as a type of microbiomes) by disputing the defense mechanism in their cell walls and make them more exposed to the attacks from our antibodies.

During the paleolithic, hominins grouped together in small societies such as bands, and subsisted by gathering  plants  and fishing, hunting or scavenging wild  animals. the paleolithic is characterized by the use of knapped stone tools, although at the time humans also used  wood  and bone tools.