The main reason of Hussain Shaheed Suhrawardy failure was?

President Iskander Mirza was a key factor in his failure.

Explanation:

After being appointed prime minister, Hussain Shaheed had previously had some disagreements with President Mirza. Hussain had several other dissidents who sat in high state positions. There was a lot of slander against him, but the most serious was that he was involved in Hindu-Muslim riots. Shaheed fell victim to the system, and that is the main reason for his failure. He died in Beirut in the political emigration of the year.

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