Where the europeans eager to trade with africa and asia

By the 1400s, merchants and crusaders had brought many goods to Europe from Africa, the Middle East, and Asia. Demand for these goods increased the desire for trade. Europeans were especially interested in spices from Asia. ... Trade with the East, however, was expensive and difficult.

well i'm late but i think its: b, c, and e

answer; i believe that the correct answer is (scientific approach)