Who is responsible for leading the federal government's response efforts to ensure that the necessary coordinating structures, leadership, and resources are applied quickly and efficiently to large-scale and catastrophic incidents?
a. secretary of homeland security
b. the president
c. fema administrator
d. dhs director of operations coordination

The President  is responsible for leading the Federal Government's response efforts to ensure that the necessary coordinating structures, leadership, and resources are applied quickly and efficiently to large-scale and catastrophic incidents.

B

Explanation:

The charges of The President include leading the effort to the response of the Federal Government.

He is also responsible in ensuring the application of necessary leadership, coordinating structures, and resources to catastrophic incidents and large scale incidents in a fast, efficient and quicker manner.  

He is responsible in setting policies for greater incidents after the consultation with the National Security Council and Homeland Security Council.

Hence, the The President is the one who takes necessary efforts in large-scale incidents.