How might you reasonably explain these differences over time? Provide support for your hypotheses.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience.b. report the adverse drug experience to the irb only if there are several other occurrences.c. report the adverse drug experience as part of the continuing review report.d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.

What was the first instrument to ever record an earthquake?

Rank the six combinations of electric charges on the basis of the electric force acting on q1. define forces pointing to the right as positive and forces pointing to the left as negative. rank positive forces as larger than negative forces. q1,q2,q3 = positive(+) q1 = + q2 = + q3 = - q1 = + q2= - q3= + q1= - q2= + q3= + q1= + q2= - q3= - q1,q2,q3 = negative