Please follow my I'd and get follow back​

Rectangle pqrs has vertices p(1, 4), q(6, 4), r(6, 1), and s(1, 1). without graphing, find the new coordinates of the vertices of the rectangle after a reflection over the x-axis and then another reflection over the y-axis.

Opium, methamphetamine, and cocaine are in the united states.

How do you apply ethical theory to provide rationale for a proposed public health intervention?