What are the hurdles in cancer immunotherapy?

While gloving prior to beginning an arthroscopic procedure, the surgeon questions the necessity for double-gloving. which of the following are the most appropriate reasons to double-glove? 1. the barrier efficacy of latex decreases over time. 2. latex has a lattice-like structure that can lead to fluid passage. 3. minimally invasive procedures increase the risk of infection. 4. double-gloving adds protection from infection due to puncture injuries. a. 1,2, and 3 only b. 1,2, and 4 only c. 1,3, and 4 only d. 2,3, and 4 only