What is inflammation and what is the underlying mechanism?

Inflammation is a response triggered by damage to living tissues. The inflammatory response is a defense mechanism that evolved in higher organisms to protect them from infection and injury. A coordinated series of common effector mechanisms of inflammation contrib- ute to tissue injury, oxidative stress, remodeling of the extracellular matrix, angiogenesis, and fibrosis in di- verse target tissues.

Explanation:

between the two muscle layers is the myenteric or auerbach's plexus, which controls peristalsis. in the colon, the muscularis externa is much thicker because the feces are large and heavy, requiring more force to push along. the stomach has a third layer of muscularis externa: the inner oblique layer.

activation of phospholipase c (plc) indirectly increases intracellular ions through inositol triphosphate (ip3).