Metabolism/Explain the differences between the Hexokinase and Glucokinase enzymes? * Your answer

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Glucokinase and Hexokinase are enzymes which phosphorylate glucose to glucose-6-phosphate, trapping glucose inside the cell. ... Hexokinase is found in most tissues. Compared to glucokinase, hexokinase has a lower Km (higher binding affinity) and lower Vmax (lower capacity).

Hexokinase is found in most tissues, has a lower Km, and is not induced by insulin, but does undergo negative feedback inhibition by glucose 6 phosphate

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