Drugs that are the most effective at treating overactive bladder increase activity

The best answer for the statement: Drugs that are most effective at treating overactive bladder increase:___ activity, would be: anticholinergic activity

Explanation:

Overactive bladder (OAB) is a condition in which, due to disordered firing of the nerves in the bladder walls, and also constant stimulation by ACH (acetylcholine), the neurotransmitter of the central nervous system that activates smooth and skeletal muscles, a person may constantly feel the need to urinate, even if the bladder has not filled to full capacity. It can become a really difficult condition to treat, but before using medication, there are a lot of  non-pharmacological treatments that are used in preference to actual chemical substances. However, when these therapies do not work, doctors will prescribe anti-cholinergic medication, which block muscarinic receptors in the muscle walls of the bladder, and thus prevent these walls from reacting to ACH. The end result is to reduce the sense of urination urgency and increase bladder retention and capacity.