Could you explain the answer pleasr

Which of the following is not a subset of {1,2,3}?

Heather is writing a quadratic function that represents a parabola that touches but does not cross the x-axis at x = -6. which function could heather be writing? fx) = x2 + 36x + 12 = x2 - 36x - 12 f(x) = -x + 12x + 36 f(x) = -x? - 12x - 36

What is the axis of symmetry of the function f(x)=-(x+ 9)(x-21)