Biopsy is often used to distinguish cancerous from harmless tumors before resorting to surgery. Ridgway et al. (2004) investigated the ability of MIB-1 monoclonal antibodies, which detect rapidly proliferating cells with staining, to distinguish known breast tumor types from biopsies on a postoperative sample. The measurements posted below were taken to determine whether the BIB-1 index measured on biopsy is associated with tumor size. The MIB-1 index was measured double-blind on histological sections of tumor tissue by the number stained cells counted at a particular microscope magnification. Based on this information, which of the following options is most appropriate A- Use Pearson's correlation coefficient with only tumor size log-transformed
B- Use Pearson's correlation coefficient on the untransformed data
C- Use Spearman's rank-based correlation on the untransformed data
D- Use Pearson's correlation coefficient with both tumor size and MIB-1 index log-transformed
E- Use Pearson's correlation coefficient with only MIB-1 index log-transformed