0=x²+4x+1

rewrite the equation by completing the square

its 4 because 2 times 2 is 4, if you double the number two you get four

ending amount = beginning amount / (2^n)

where "n" = number of half-lives (or elapsed time / half-life)

ending amount = 50 mg / (2 ^10 / 5.3)

ending amount = 50 mg / (2 ^ 1.8867924528)

ending amount = 50 m / 3.6981210597

ending amount = 13.5203794557 mg

or about 13.5 mg remain

source: