Only affected individuals are shaded. what is the most likely mode of inheritance? pedegree: row i shows two couples none of which are affected (labedled as follows: female 1, male 2, female 3, male 4). row 2 two offspring per couple, female 5 is affected and sister to male 6 who is married to female 7, who is sister to female 8, who is also affected. row 3 shows the third generation. individual 9 is an unaffected female.