Which part of the constitution

Expressed powers.

Explanation:

The interstate commerce clause is one of the federal government's expressed powers, which are: the power to tax, to borrow money, to regulate commerce and currency, to declare war, and to raise armies and maintain the navy.

i think it can have both positive and negative effects on businesses.

for example:

lets say you own a small business and taxes go up 4% that means it is going to cost your business more money to buy product to sell. but at the same time you make more money from the tax rise.

that is my theory.

your answer would be a. true