John c. calhoun is best described as a. a two-time vice president who supported slavery and states’ rights. b. a massachusetts senator who was antislavery but supported compromise. c. a president who declared that nullification was a form of treason.,

Calhoun was Vice President under the administration of John Quincy Adams, and stayed on with Andrew Jackson after Adam was defeated during the election of 1828. A native of South Carolina, Calhoun was known for being a strong proponent of slavery in the South. As such, the best answer would be A. "A two-time vice president who supported slavery and states' rights".

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