The preemption act most directly dealt with
(a) the sale of government land
(b) the right of the united states to attack nations perceived as a threat
(c) the passage of strict slave laws to suppress future slave uprisings
(d) the federal government’s right to remove native americans from
lands planned for future expansion
(e) the states’ right to nullify federal mandates

The Preemption Act most directly dealt with A) THE SALE OF GOVERNMENT LAND.

The Preemption Act of 1841 was a federal law approved on September 4, 1841. It is also known as the Distributive Preemption Act. This Act  permitted "squatters" who were living on federal government owned land to purchase up to 160 acres  at a very low price; not less than $1.25 per acre,  before the land was to be offered for sale to the general public.

Ibelieve the answer is the  third option, or c.