During the presidency of george washington,
disagreements between alexander hamilton and
thomas jefferson over the interpretation of the
constitution contributed to the
(1) impeachment of federal judges
(2) defeat of the whiskey rebellion
(3) formation of political parties
(4) elimination of the commerce clause

During the presidency of George Washington, disagreements between Alexander Hamilton and Thomas Jefferson over the interpretation of the Constitution contributed to the "(3) formation of political parties," since Jefferson wanted there to be far "less" government involved in every-day life, while Hamilton thought the government should act as a powerful tool.