What was an impediment to westward travel because of arkansas' location on the west side of the mississippi?

The impediment to the westward travel because of Arkansas’ location to the west side of the Mississippi was that the Indians were likely to be at the expense of the Europeans because of it, in which they are likely to be harmed.

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the scientific revolution brought us a renewed understanding of humanity and our place in the universe, new scientific equipment, and new laws as a basis for future scientific discovery.