How did the missouri compromise impact the future of north-south relations in the u. s.?

The Missouri compromise was about whether slavery should continue a part of American society. It allowed the state of Missouri to become a part of the union while retaining slavery, balanced by admitting Maine, which was a free state. It also prohibited slavery in the new Louisiana Purchase states. It was considered deeply flawed on both sides, and merely established the differences that would later lead to war. 
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It was a combination of conquests and alliances