What was the first "intervening obstacle" which hindered american settlement of the interior continent?

On july 4, 1776, thomas jefferson wrote the declaration of independence. the declaration of independence can be compared to a break up letter because jefferson explained why america wanted its independence from king george iii. read pages 516-520 in your textbook to discover why america wanted to be an independent country. you will write your own break up letter from the colonies to king george iii. your letter needs to be at least 5-7 sentences, include the issues/events leading up to this breaking point, and why the founding fathers felt independence would be better. remember! this is a “breakup letter”, so channel your inner taylor swift and make it creative!