Which is one reason southern states were generally opposed to the ratification of the constitution A. They disagreed with the three-fifths compromise
B. They wanted to form a separate republics
C. They did not agree with anti-federalist
D. They were concerned about equal rights for enslaved people

while it was true that the cotton gin reduced the labor of removing seeds, it did not reduce the need for slaves to grow and pick the cotton.

explanation:

before eli whitney's invention of the cotton gin, picking and cleaning cotton was a slow, labor-intensive job. workers, usually slaves, had to pick the seeds from the cotton fibers by hand. this invention made it possible to grow large amounts of cotton on big farms and make money.