What led to the political confusion that took place after Pax romana?

the andes or andean mountains (spanish: cordillera de los andes) are the longest continental mountain range in the world, forming a continuous highland along the western edge of south america. this range is about 7,000 km (4,300 mi) long, about 200 to 700 km (120 to 430 mi) wide (widest between 18° south and 20° south latitude), and of an average height of about 4,000 m (13,000 ft). the andes extend from north to south through seven south american countries: venezuela, colombia, ecuador, peru, bolivia, chile and argentina.

from wikipedia

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answer; i believe that the correct answer is (tobacco);

necessary and proper clause. the congress shall have power to all laws which shall be necessary and proper for carrying into execution the foregoing powers, and all other powers vested by this constitution in the government of the united states, or in any department or officer thereof.