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1. Cause:

Increased demand for land west of the Appalachian. Increased number of "pilgrims" to the west. Annexation of Texas by the Federal Government.

2. Cause:

Need for more land for western settlers. National "Manifest Destiny" dream. US and Britain settlement.

3. Cause:

Cessation of south-western territories to the US. Increased land mass and space for settlers.

disease was the number one killer of native peoples. they had had little exposure to the diseases of europe. this led to some villages being almost completely wiped out and some tribes destroyed.