This single disease was the most serious obstacle to European conquest of the tropical world, responsible for thousands of settler deaths
throughout the eighteenth and nineteenth centuries.
http://www. pbs. org/gunsgermssteel/variables/malari a. html
The discovery of which drug was most responsible in addressing the
problem posed in this excerpt?

for starters, there is the structural trend of rising primary government expenditure as a share of gdp, which reached 36% in 2014, up from 22% in 1991. this increase reflected a political desire to address the poverty and inequality that had gone unaddressed during previous decades. to support the increase, brazil’s government increased taxes on consumption and promoted progress toward labor-market formalization. nonetheless, public investment, particularly in infrastructure, took a hit. in fact, with the exception of the 2005-2008 period, total investment as a share of gdp has remained below 20% since 1991.

articles of confederation

it took two men to wrestle rome back from chaos and turn a republic into an empire. in the first century bc, rome was a republic. power lay in the hands of the senate, elected by roman citizens. but the senators were fighting for power between themselves.