Small groups of European explorers defeated indigenous people of the Americas. Which of these factors made that possible? Choose all that apply. 1. The Europeans tricked, cheated, and enslaved them. 2. Smallpox and other European diseases weakened them. 3. They died of scurvy after eating nothing but leather and rats to survive. 4. Some indigenous people worked against their own to help the Europeans. 5. Cultural differences, including animals, weapons, and religion, confused and scared them.