In detail the impact of tobacco had on both the economy and labor force in virginia as well as the impact of tobacco had on relations with native americans?

Tobacco in the American Colonies was what was considered a "cash crop". It didn't grow well in most places, therefore it was valuable for its' rarity. Virginia marshes and humidity became the perfect place for tobacco to be cultivated.
As a result, large tobacco plantations were a key establishment there. However, with such a high demand, a greater work force was needed. It came in the form of indentured servants, and even more commonly, slave labor.
The Native Americans used tobacco for ceremonial purposes. However, they had a greater belief in protecting the land. While the tobacco industry could have been used in a way that would have improved relationships with the Natives, it wasn't. 
The Colonists expanded further and further onto Native American land, causing increased tensions between the two groups and a rise in the amount of conflicts.

South carolina was so angry about the election of lincoln that they seceded from the union on december 20, 1860. they attacked fort sumter later, on april 12, 1861.