How did europe's desire for an ocean route to asia shape its contacts with africa?

After the ottomans blocked the Europeans trade routes to the Indian subcontinent and the rest of Asia Europe had to find an ocean route around Africa which put them in contact with many indigenous populations which the Europeans would colonize and enslave in order to exploit the routes they had to take to get to Asia 

They were eliminating problems caused by industrialization, urbanization, immigration, and corruption in government