From the information about pre-Columbian civilizations in the 15th century, which conclusion can be supported? The Spanish entered an area of economic and political disorder. The cultures in Mexico and South America were flourishing prior to Spanish rule. The Aztecs and Incas were locked in economic competition. The Incas were poised to overcome the Aztecs were it not for the Spanish.

Guyana is bordered by the Atlantic Ocean to the north, by Suriname (along the Courantyne River) to the east, by Brazil to the south and southwest, and by Venezuela to the west.

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.