kinaharap ni Quezon sa kanyang pag upo bilang pangulo ang mga pagbabagong dulot ng pananakop ng mga amerikano​ at ang mga suliraning ( panlipunan at pangkabuhayan, politikal at pang ekonomiya) ng bansa.

travels along an axon. this triggers a wave of electrical activity that passes from the cell body along the length of the axon to the synapse

the colonial period, since this was a time of mass immigration from a variety of people from europe.