The Roman war with who resulted in Rome becoming the most powerful state in the Mediterranean

The Punic Wars

Explanation:

The three Punic Wars between Carthage and Rome took place over nearly a century, beginning in 264 B.C. and ending in Roman victory with the destruction of Carthage in 146 B.C. By the time the First Punic War broke out, Rome had become the dominant power throughout the Italian peninsula, while Carthage–a powerful city-state in northern Africa–had established itself as the leading maritime power in the world.

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