Where did the Spanish establish most of their missions in the Americas? A.)in the eastern half of South America
B.)in the southern regions of North America
C.)in the Aztec empire
D.)in the Inca empire

I believe it is A but please give me a low star if i am wrong  

B

Explanation:

They really were only focused on the southern regions of North America. But remember they were really trying to find the Northwest passage that did not exist,but they had no way of knowing this.

explanation:

cause they can