What was a key concern that led to a greater desperation of church and state ?? pleaseee helppp

In the late fifteenth century, a major world power that established colonies in the era of old imperialism was france or germany or spain. their colonial activity was mainly limited to america or africa or asia.

Is the choices or no ?

Is the keeping of the rights and freedoms of the people because people need their rights to survive and people need freedom not being locked in a type of prison where they can't-do something they're allowed to do. freedom is given to everyone when they're born

Mesopotamia an area geographically located between the tigris and euphrates rivers. mesopotamia means the land between two rivers.