How did the “America’s” change during Columbus’s lifetime as a result of his voyages?

Columbus showed Europeans the way to America.

Explanation:

With the expedition of Christopher Columbus, there started an exchange of plants, animals, and diseases, and a mix of cultures that had a long term impact on the New word and Europe. He changed the world by introducing colonialism to the American continent which in turn contributed to the extinction of many of North and South America's indigenous peoples and cultures. The native population was wary of the invaders and frequently fought aggressively against giving up their resources to the Europeans. However, diseases such as smallpox devastated the indigenous populations to such an extreme that the colonization happened easily.

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