How did pioneer trails and the settlers who traveled them negatively affect American Indians? Check all that apply. scared away wild game polluted sources of water refused to trade for resources brought diseases west

Pioneers who passed through Native American lands were constantly disrupting the lives of the Natives. They took land that wasn't theirs, killed wild life without respect to breeding seasons or the hierarchy of the animal chain, some looted the Native burial sites, killed Native people out of fear or started wars by not understanding the ways of the Natives or not following the treaties set out by the government. By killing wild life, the pioneers removed food from the Natives. When the pioneers damaged the Great Plains so the buffalo could no longer find food there, the Natives went hungry. To make sure the settlers and pioneers were safe, troops moved the Native Americans from lands that were historically theirs.

there is not all the infomation needed to answer this question.   we need the who was going, or we need to know what islands you are talking about.