What principle did the southern states say justified leaving the union (of the United States)?

The virginia plan was primarily drafted by james madison.

Ibelieve it belongs to the president.

True blindness may be caused by trauma to the eye, severe conjunctivitis due to  ibr (infectious bovine rhinoceros) or pink eye or other infections, leptospirosis, lead poisoning, selenium toxicity, fungal infections, vitamin a  deficiencies, rabies, vitamin b12 deficiency, neoplastic of the orbit or  conjunctiva, cataracts, congenital malformations, etc.