Constantinople was a thriving city in the 1200s mainly because of its location on a major trade route between

Asia and eastern Europe

Explanation:

Constantinople was a thriving city in the 1200s mainly because of its location on a major trade route between Asia and eastern Europe.

Constantinople was the capital city of the Roman Empire.

It was first settled in the seventh century B.C.

It was a symbol of the rise of Islam and the fall of the center of Christianity.

It connects the Black Sea with the Mediterranean Sea.