The control of most trade between asia and europe in the 1400s by arab and italian merchants caused by

Europeans outside Italy to search for direct access to Asia, is the right answer.

Explanation:

Though Arab and Italian merchants were involved in the trade with Asia for centuries, their involvement in trade with Asia extensively grew during the 1400's as the population of Europe began to grow and their demand for goods also grew. The most demanded items were the spices to preserve the food for a long time. During this time, the Arab and the Italian merchants establish their control over the trade of Asia and Europe. The Arab merchants took the goods to the Mediterranean and exchanged them with the Italian merchants. In this system, Italian merchants had to be dependent on the supply of the Arabs accordingly the supply of such goods in the European market was limited. Since the supply was limited those merchants charged the people very high for their supply. As a result of this Europeans outside Italy to search for direct access to Asia.