What was the major effect of axum’s isolation from trade?

Commanded both the Nile's north-south trade route and the east-west trade routes from the Red Sea to North Africa Location was the major reason for its development into successful center of ... Nubia was overwhelmed

Axum isolated himself distancing himself from Europe and for religious reasons he turned away from many former business partners. Later Axum prospered because they controlled the Red Sea. The kingdom of Axum extended its reach to the mountains of modern Ethiopia on the shores of the Red Sea. It was the second state that developed in tropical Africa. Axum became an important center of commerce, particularly in the traffic of ivory.

doat means to cherish based on the key word fancying and that it is a living thing