Suppose you are interested in the effects on boys of different dosages of a new drug to treat adhd. you set up an experiment to consider the factor of dosage with two levels (300 mg vs. 500 mg). which would be the best choice for the different treatment groups of the experiment within each block? a. three groups: no drug, 300 mg of new drug, 500 mg of new drug. b. two groups: placebo drug and either 300 mg of new drug or 500 mg of new drug. c. four groups: no drug, placebo drug, 300 mg of new drug, 500 mg of new drug. d. three groups: placebo drug, 300 mg of new drug, 500 mg of new drug. e. two groups: 300 mg of new drug and 500 mg of new drug.

Summarize the neurobiology of addiction section in 3-4 sentences. summarize the evolutionary history of cravings in 3-4 sentences. then explain how the "science of getting hooked" article, and these issues, relate to your own life. then connect this discussion to recreational marijuana. new york state is getting very close to legalizing recreational marijuana, which is why they carried out the above study on potential impact of regulation. what are the potential health impacts cited in the above study if marijuana were to be regulated in ny? how do you think addiction would be impacted by regulated marijuana? considering what you now know about the brain, body and addiction, what are your thoughts on legalization of recreational marijuana in new york state?

A35-year-old woman comes to the ed complaining of chest pressure. she has had such episodes intermittently over the last 5 years, usually when sleeping, but over the last year she has had more frequent severe symptoms that are occasionally associated with severe migraine headaches. the pain is midsternal and is described as pressure that extends as a band around her chest. the ed physician is initially dubious that the pain is cardiac in origin, because the woman has no coronary disease risk factors. an ecg, however, shows 2mm st-segment elevation and inverted t waves in leads v1 through v5 and 1mm st-segment depression in leads ii, iii, and avf. before the cardiologist arrives in the ed, the patient's ecg has returned to normal. this repeat normal ecg is obtained after the administration of aspirin, nitroglycerin, morphine, and oxygen. which of the following is most likely for these findings? - diffuse intimal thickening with focal areas of atherosclerotic narrowing - intermittent thrombus formation and lysis in the left anterior descending artery - intermittent thrombus formation and lysis in the right coronary artery - plaque rupture and thrombus formation in the left anterior descending artery - transiently increased coronary vascular tone in the right coronary artery

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for