The system responsible for defense against infection and disease is the

THe immune system is held responsible for protecting against infection and diseases in the body

Smoking damages the respiratory system by inhalation of a foreign substance, that is absorbed and residue is left behind on our lungs sponge like substance. the gas that is inhaled also increase your blood pressure and dilates your blood vessels. also the process of inhaling and exhaling the smoke it causes irritation to the throat and mouth. smoking can cause lung cancer and other respiratory and circulatory diseases. 

My funny joke is my friend can no roll over