Explain how general health and mental well-being might affect the immune system.

The immune system may be affected by stress, which leads to changes in the endocrine and nervous systems. In the endocrine system, physical and emotional stress can cause the adrenal glands to secrete hormones that affect the numbers of white blood cells. In the nervous system, neurotransmitters secreted when we are relaxed and happy may enhance immunity, while stress may lower it.

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