Vasoconstriction occurs when epinephrine (adrenaline) binds to the a-adrenergic receptor on vascular smooth muscle cells. One approach to treating high blood pressures is to administer competitive inhibitors that bind to the a-adrenergic receptor. The Kd for binding of epinephrine to this receptor is ~0.6 mM. Which compounds might be a good candidate drug for high blood pressure?

Match each disease with the body system it affects

An 80-year-old woman comes to the urgent care clinic with dyspnoea on exertion. on physical examination, her blood pressure is 100/70, and her pulse is 75. she has no pulsus paradoxus. her jugular veins are distended, and she has distant heart sounds. in addition, she has extra third and fourth heart sounds. her liver is enlarged, and she has pedal oedema. she has occasional premature ventricular contractions on her electrocardiogram. a chest x-ray reveals clear lung fields with a dilated cardiac silhouette. her echocardiogram reveals ventricular walls with a "speckled pattern". which of the following is the most likely diagnosis? - alcoholic cardiomyopathy- amyloidosis- haemochromatosis- tuberculosis- viral myocarditis

Explain the importance of getting and proper treatment for a mental illness.