You find a suspicious breast lump during your annual physical examination for a 42-year-old pediatrician. You tell her she will be scheduled to see a breast specialist as soon as possible. While she nods and seems to agree with your plan, she appears distracted. At this point you say, "You seem a bit distracted right now." Which of the following continuations is recommended to move you forward in partnership?a. I wonder what you are thinking about all this?b. Are you ready to move ahead with further evaluation and treatment?c. What do you already know about what such masses might represent?d. While awaiting diagnosis, what kind of support do you have from family or friends?e. I’d like to recheck your pulse and BP before we move on."

Spherocytosis is an inherited blood disease in which the erythrocytes (red blood cells) are spherical instead of biconcave. this condition is inherited in a dominant fashion, with sph- dominant to sph+. in people with spherocytosis, the spleen "reads" the spherical red blood cells as defective, and it removes them from the bloodstream, leading to anemia. the spleen in different people removes the spherical erythrocytes with different efficiencies. some people with spherical erythrocytes suffer severe anemia and some mild anemia, yet others have spleens that function so poorly there are no symptoms of anemia at all. when 2400 people with the genotype sph- sph+ were examined, it was found that 2250 had anemia of varying severity, but 150 had no symptoms. does this description of people with spherocytosis represent incomplete penetrance, variable expressivity, or both? explain your answer. (3 points)

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